Run Ronnie Run! not only features David Cross and Bob Odenkirk, but supporting roles and cameos from Nikki Cox, EJ De La Pena, R. Lee Ermey, M.C. Gainey, Thomas J. Kenny, David M. Koechner and Jill Talley, along with a number of celebrity cameos that include Dave Foley, Andy Richter, Rebecca Romijn-Stamos, John Stamos, Kathy Griffin, Scott Thompson, Mandy Patinkin, Matt Stone, Trey Parker, Laura Kightlinger, Patrick Warburton and Garry Shandling.

The DVD includes a widescreen (1.85:1) version of the film, Dolby Digital 5.1 Surround Sound, Stereo Surround Sound, English subtitles, closed captions and animated menus. The DVD will also feature deleted scenes, the Three Times One Minus One music video, lots of hidden Easter eggs, the trailer for the film as well as trailers for other New Line Home Entertainment films.

Recognizing a media star when he sees one, Terry Twillstein (Odenkirk), a late-night pitchman with big dreams, sets out for Doraville to spring Ronnie from his latest stint in jail and persuade him to go to Hollywood to star in his very own TV show. A show that will make the most of Ronnie’s talent for being in the wrong place at the wrong time. With the promise of fame – and lots of free beer – Ronnie heads to Hollywood with Terry to embark on an adventure of high-speed chases, brawls and handcuffs caught on tape. Soon, Ronnie is a national TV star and the toast of Hollywood, but he slowly comes to discover that fame and fortune aren’t exactly what he thought they would be.